Blood Coagulation Failure in Obstetrics

Disseminated Intravascular Coagulation Syndromes in Obstetrics.

Disseminated intravascular coagulation (DIC) is a syndrome that can be initiated by a myriad of medical, surgical, and obstetric disorders. Also known as consumptive coagulopathy, DIC is a common contributor to maternal morbidity and mortality and is associated with up to 25% of maternal deaths. The etiopathogenesis of DIC is complex and currently thought to be initiated by tissue factor or thr...

Blood transfusion in obstetrics.

Transfusion of blood and blood components is a common practice in obstetric wards but it is not without risk. The incidence of transfusion reactions varies from 4 in every hundred transfusions for non-haemolytic reactions to one in every 40,000 for haemolytic transfusion reactions. The physiological basis of blood transfusion is outlined in this article. Most of the donated blood is processed i...

Blood component therapy in obstetrics.

Hemorrhage is the leading cause of intensive care unit admission and one of the leading causes of death in the obstetric population. This emphasizes the importance of a working knowledge of the indications for and complications associated with blood product replacement in obstetric practice. This article provides current information regarding preparation for and administration of blood products...

Changes in blood coagulation.

Studies in Blood Coagulation

Description is given of changes in blood coagulability found in diseases of the rabbit, including malignant tumor, spontaneous infections, non-bacterial diseases and lesions, and hemorrhagic states specifically induced. The changes involved variously the time of onset of blood coagulation, clot formation rate and the rate and extent of clot retraction.